Biosensors-based approaches for other viral infection detection

Contamination and infection due to viruses are one of the major reasons for diseases amounting to hundreds of thousands of deaths every year. In recent years, several novels and reemerging viral diseases have seen an outstanding rise in occurrence like coronavirus disease 2019 (COVID-19) which has arguably altered the socioeconomic strata and also pointed out the shortcomings in medical biology and diagnostics at a global scale. The overwhelming burden of global infection numbers exceeded expectations from federal healthcare programs and medical facilities. The current situation pointed out that the cost of reliable tests is disproportionately high in case of frequent repetition of tests on one person. Also, the speed of distribution, implementation, and evaluation of tests are unsatisfactory in the current situation, both technically and logistically. Viruses are nonliving obligate parasites and require living host cells to replicate and propagate. Due to their error-prone replication mechanism and fast mutations, the protective layers and mechanisms change quickly, thus helping them to evade immune reactions in the host cell. This has led to reemergence and also establishing new virus strains. Medicinal biology and conventional diagnostic practices are now facing a challenging task to upkeep with the pace of these occurrences. Therefore to improve the quality of detection and to help in the reduction of cost, major advancements are required in the detection techniques to better prepare the healthcare system for a similar novel virus infection in the future.