Selective chemical tracking of Dnmt1 catalytic activity in live cells

Enzymatic methylation of cytosine to 5-methylcytosine in DNA is a fundamental epigenetic mechanism involved in mammalian development and disease. DNA methylation is brought about by collective action of three AdoMet-dependent DNA methyltransferases, whose catalytic interactions and temporal interpla...

Descripción completa

Detalles Bibliográficos
Autores principales: Stankevičius, Vaidotas, Gibas, Povilas, Masiulionytė, Bernadeta, Gasiulė, Liepa, Masevičius, Viktoras, Klimašauskas, Saulius, Vilkaitis, Giedrius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901439/
https://www.ncbi.nlm.nih.gov/pubmed/35245449
http://dx.doi.org/10.1016/j.molcel.2022.02.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901439/
https://www.ncbi.nlm.nih.gov/pubmed/35245449
http://dx.doi.org/10.1016/j.molcel.2022.02.008

Ejemplares similares