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Talimogene Laherparepvec: Moving From First-In-Class to Best-In-Class

Talimogene laherparepvec (T-VEC) is a modified oncolytic herpes Simplex virus, type 1 (HSV-1) encoding granulocyte-macrophage colony stimulating factor (GM-CSF). T-VEC is adapted for selective replication in melanoma cells and GM-CSF was expressed to augment host anti-tumor immunity. T-VEC is indica...

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Detalles Bibliográficos
Autores principales:	Kaufman, Howard L., Shalhout, Sophia Z., Iodice, Gail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901478/ https://www.ncbi.nlm.nih.gov/pubmed/35274007 http://dx.doi.org/10.3389/fmolb.2022.834841

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