Cargando…

Extracellular vesicle neurofilament light is elevated within the first 12-months following traumatic brain injury in a U.S military population

Traumatic brain injury (TBI) can be associated with long-term neurobehavioral symptoms. Here, we examined levels of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in extracellular vesicles isolated from blood, and their relationship with TBI severity and neurobehavioral s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guedes, Vivian A., Lange, Rael T., Lippa, Sara M., Lai, Chen, Greer, Kisha, Mithani, Sara, Devoto, Christina, A. Edwards, Katie, Wagner, Chelsea L., Martin, Carina A., Driscoll, Angela E., Wright, Megan M., Gillow, Kelly C., Baschenis, Samantha M., Brickell, Tracey A., French, Louis M., Gill, Jessica M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901614/ https://www.ncbi.nlm.nih.gov/pubmed/35256615 http://dx.doi.org/10.1038/s41598-022-05772-0

Ejemplares similares

APOE Is Associated With Serum Tau Following Uncomplicated Mild Traumatic Brain Injury
por: Lippa, Sara M., et al.
Publicado: (2022)

Objective and Subjective Auditory Effects of Traumatic Brain Injury and Blast Exposure in Service Members and Veterans
por: Kuchinsky, Stefanie E., et al.
Publicado: (2020)

P111 Sleep disturbances are associated with poor neurobehavioural outcomes following traumatic brain injury: A study of military service members and veterans
por: Pattinson, C, et al.
Publicado: (2021)

Extracellular vesicle concentrations of glial fibrillary acidic protein and neurofilament light measured 1 year after traumatic brain injury
por: Flynn, Spencer, et al.
Publicado: (2021)

Extracellular Vesicle Proteins and MicroRNAs as Biomarkers for Traumatic Brain Injury
por: Guedes, Vivian A., et al.
Publicado: (2020)

Extracellular Vesicle Proteins and MicroRNAs Are Linked to Chronic Post-Traumatic Stress Disorder Symptoms in Service Members and Veterans With Mild Traumatic Brain Injury
por: Guedes, Vivian A., et al.
Publicado: (2021)

Sex Differences in Behavioral Symptoms and the Levels of Circulating GFAP, Tau, and NfL in Patients With Traumatic Brain Injury
por: Sass, Dilorom, et al.
Publicado: (2021)

Cytokine Profiles Differentiate Symptomatic from Asymptomatic PTSD in Service Members and Veterans with Chronic Traumatic Brain Injury
por: Smith, Ethan G., et al.
Publicado: (2022)

Extracellular Vesicle Levels of Nervous System Injury Biomarkers in Critically Ill Trauma Patients with and without Traumatic Brain Injury
por: Guedes, Vivian A., et al.
Publicado: (2022)

Poor Sleep Quality is Linked to Elevated Extracellular Vesicle-Associated Inflammatory Cytokines in Warfighters With Chronic Mild Traumatic Brain Injuries
por: Gottshall, Jackie L., et al.
Publicado: (2022)

Circulating Brain Injury Exosomal Proteins following Moderate-to-Severe Traumatic Brain Injury: Temporal Profile, Outcome Prediction and Therapy Implications
por: Mondello, Stefania, et al.
Publicado: (2020)

Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content
por: Elder, Gregory A., et al.
Publicado: (1998)

Inflammation Relates to Chronic Behavioral and Neurological Symptoms in Military Personnel with Traumatic Brain Injuries
por: Devoto, Christina, et al.
Publicado: (2017)

Textiles del mundo islámico /
por: Gillow, John
Publicado: (2010)

Elevated Axonal Protein Markers Following Repetitive Blast Exposure in Military Personnel
por: Vorn, Rany, et al.
Publicado: (2022)

Neuronally-derived tau is increased in experienced breachers and is associated with neurobehavioral symptoms
por: Edwards, Katie A., et al.
Publicado: (2021)

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density
por: Rao, Mala V., et al.
Publicado: (2002)

Predictive Value of Serum Neurofilament Light Chain Levels in Anti-NMDA Receptor Encephalitis
por: Brenner, Juliette, et al.
Publicado: (2023)

Inflammatory Cytokines Associate With Neuroimaging After Acute Mild Traumatic Brain Injury
por: Edwards, Katie A., et al.
Publicado: (2020)

Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments
por: He, Yan, et al.
Publicado: (2005)

Neurofilament light chain: defining the analyte
por: Leckey, Claire A., et al.
Publicado: (2022)

Differential dynamics of neurofilament-H protein and neurofilament-L protein in neurons
Publicado: (1994)

Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene
Publicado: (1993)

Alcohol and Stress in the Military
por: Schumm, Jeremiah A., et al.
Publicado: (2012)

Military service and alcohol use: a systematic narrative review
por: Osborne, A K, et al.
Publicado: (2022)

A motor for neurofilaments
por: Dove, Alan W.
Publicado: (2002)

Antibody decoration of neurofilaments
Publicado: (1981)

Partial purification of neurofilament subunits from bovine brains and studies on neurofilament assembly
Publicado: (1981)

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments
por: Ackerley, Steven, et al.
Publicado: (2003)

Requirement of Heavy Neurofilament Subunit in the Development of Axons with Large Calibers
por: Elder, Gregory A., et al.
Publicado: (1998)

Plasma neurofilament light chain concentration is increased in anorexia nervosa
por: Nilsson, Ida A. K., et al.
Publicado: (2019)

Blood Neurofilament Light Chain: The Neurologist’s Troponin?
por: Thebault, Simon, et al.
Publicado: (2020)

Depression and anxiety disorders in patients with multiple sclerosis: association with neurodegeneration and neurofilaments
por: Tauil, C.B., et al.
Publicado: (2021)

Neurofilament-dependent Radial Growth of Motor Axons and Axonal Organization of Neurofilaments Does Not Require the Neurofilament Heavy Subunit (NF-H) or Its Phosphorylation
por: Rao, Mala V., et al.
Publicado: (1998)

Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport
Publicado: (1996)

Plasma Neurofilament Light Chain Levels Are Elevated in Children and Young Adults With Wolfram Syndrome
por: Eisenstein, Sarah A., et al.
Publicado: (2022)

The role of neurofilament transport in the radial growth of myelinated axons
por: Nowier, Rawan M., et al.
Publicado: (2023)

Military vaccines in today’s environment
por: Schmaljohn, Connie S., et al.
Publicado: (2012)

Neurofilament light chain: a biomarker for genetic frontotemporal dementia
por: Meeter, Lieke H., et al.
Publicado: (2016)

White Matter Hyperintensities Are Not Related to Symptomatology or Cognitive Functioning in Service Members with a Remote History of Traumatic Brain Injury
por: Lippa, Sara M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mbart8u0l6na4n99pinhprjrn8