Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers

Primary or acquired therapy resistance is a major obstacle to the effective treatment of cancer. Resistance to apoptosis has long been thought to contribute to therapy resistance. We show here that recombinant TRAIL and CDK9 inhibition cooperate in killing cells derived from a broad range of cancers...

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Detalles Bibliográficos
Autores principales: Montinaro, Antonella, Areso Zubiaur, Itziar, Saggau, Julia, Kretz, Anna-Laura, Ferreira, Rute M. M., Hassan, Omar, Kitzig, Ella, Müller, Ines, El-Bahrawy, Mona A., von Karstedt, Silvia, Kulms, Dagmar, Liccardi, Gianmaria, Lemke, Johannes, Walczak, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901660/
https://www.ncbi.nlm.nih.gov/pubmed/34535764
http://dx.doi.org/10.1038/s41418-021-00869-x

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