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A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site

To investigate local tissue responses to infection we have developed a human model of killed Streptococcus pneumoniae challenge by intradermal injection into the forearm. S. pneumoniae intradermal challenge caused an initial local influx of granulocytes and increases in TNF, IL6 and CXCL8. However,...

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Detalles Bibliográficos
Autores principales:	Szylar, Gabriella, Wysoczanski, Riccardo, Marshall, Helina, Marks, Daniel J. B., José, Ricardo, Ehrenstein, Michael R., Brown, Jeremy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901783/ https://www.ncbi.nlm.nih.gov/pubmed/35256717 http://dx.doi.org/10.1038/s41598-022-07914-w

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