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Melatonin abolished proinflammatory factor expression and antagonized osteoarthritis progression in vivo

Progressive structural changes in osteoarthritis (OA) involve synovial inflammation and angiogenesis, as well as activation of the proinflammatory cytokines tumor necrosis factor alpha (TNF-α) and interleukin (IL)-8, and the angiogenic factor vascular endothelial growth factor (VEGF). The endogenous...

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Detalles Bibliográficos
Autores principales: Liu, Shan-Chi, Tsai, Chun-Hao, Wang, Yu-Han, Su, Chen-Ming, Wu, Hsi-Chin, Fong, Yi-Chin, Yang, Shun-Fa, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901806/
https://www.ncbi.nlm.nih.gov/pubmed/35256585
http://dx.doi.org/10.1038/s41419-022-04656-5