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Restoration of FMRP expression in adult V1 neurons rescues visual deficits in a mouse model of fragile X syndrome

Many people affected by fragile X syndrome (FXS) and autism spectrum disorders have sensory processing deficits, such as hypersensitivity to auditory, tactile, and visual stimuli. Like FXS in humans, loss of Fmr1 in rodents also cause sensory, behavioral, and cognitive deficits. However, the neural...

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Detalles Bibliográficos
Autores principales: Yang, Chaojuan, Tian, Yonglu, Su, Feng, Wang, Yangzhen, Liu, Mengna, Wang, Hongyi, Cui, Yaxuan, Yuan, Peijiang, Li, Xiangning, Li, Anan, Gong, Hui, Luo, Qingming, Zhu, Desheng, Cao, Peng, Liu, Yunbo, Wang, Xunli, Luo, Min-hua, Xu, Fuqiang, Xiong, Wei, Wang, Liecheng, Li, Xiang-yao, Zhang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901859/
https://www.ncbi.nlm.nih.gov/pubmed/34714519
http://dx.doi.org/10.1007/s13238-021-00878-z