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Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry

Breast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2− early-stage breast cancers to help adjuvant chemotherapy decision by providing a Recurrent Score (RS). RS measures the expression of 21 specific genes from tumor tissue, inclu...

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Detalles Bibliográficos
Autores principales: Selmani, Zohair, Molimard, Chloé, Overs, Alexis, Bazan, Fernando, Chaigneau, Loic, Dobi, Erion, Meneveau, Nathalie, Mansi, Laura, Paillard, Marie-Justine, Meynard, Guillaume, Viot, Julien, Algros, Marie-Paule, Borg, Christophe, Feugeas, Jean-Paul, Pivot, Xavier, Prétet, Jean-Luc, Curtit, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901910/
https://www.ncbi.nlm.nih.gov/pubmed/35256657
http://dx.doi.org/10.1038/s41598-022-07593-7