Cargando…

Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling

Glycoprotein prostaglandin D2 synthase (PTGDS) is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport. PTGDS has been involved in various cellular processes including the tumorigenesis of solid tumors, yet its role in carcinogenesis is contradi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Shunfeng, Ren, Shuai, Cai, Yiqing, Liu, Jiarui, Han, Yang, Zhao, Yi, Yang, Juan, Zhou, Xiangxiang, Wang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901925/ https://www.ncbi.nlm.nih.gov/pubmed/34743203 http://dx.doi.org/10.1038/s41418-021-00880-2

Ejemplares similares

P1210: TARGETING PTGDS AS A NOVEL THERAPEUTIC APPROACH IN PERIPHERAL T CELL LYMPHOMA THROUGH REGULATING IRON METABOLISM
por: Hu, Shunfeng, et al.
Publicado: (2023)

Circulating Exosomal MiR-107 Restrains Tumorigenesis in Diffuse Large B-Cell Lymphoma by Targeting 14-3-3η
por: Liu, Jiarui, et al.
Publicado: (2021)

Inhibition of Polo-like kinase 4 induces mitotic defects and DNA damage in diffuse large B-cell lymphoma
por: Zhao, Yi, et al.
Publicado: (2021)

Derivation and validation of a lipid-covered prognostic model for mature T-cell lymphomas
por: Lu, Tiange, et al.
Publicado: (2021)

Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma
por: Cai, Yiqing, et al.
Publicado: (2023)

PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations
por: Hu, Shunfeng, et al.
Publicado: (2023)

SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma
por: Jiang, Pinping, et al.
Publicado: (2021)

Glycoprotein nonmetastatic melanoma protein B accelerates tumorigenesis of cervical cancer in vitro by regulating the Wnt/β-catenin pathway
por: Xu, Shuxiang, et al.
Publicado: (2018)

ENKUR recruits FBXW7 to ubiquitinate and degrade MYH9 and further suppress MYH9‐induced deubiquitination of β‐catenin to block gastric cancer metastasis
por: Liu, Jiahao, et al.
Publicado: (2022)

STAT3 Targets Suggest Mechanisms of Aggressive Tumorigenesis in Diffuse Large B-Cell Lymphoma
por: Hardee, Jennifer, et al.
Publicado: (2013)

MYH9 nephropathy
por: Oh, Taehoon, et al.
Publicado: (2015)

Single-cell transcriptome analysis profiles the expression features of TMEM173 in BM cells of high-risk B-cell acute lymphoblastic leukemia
por: Cai, Yiqing, et al.
Publicado: (2023)

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis
por: van Veelen, Wendy, et al.
Publicado: (2011)

Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis
por: Yu, Junhui, et al.
Publicado: (2020)

STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/β-Catenin Signaling
por: Xie, Min, et al.
Publicado: (2021)

Sex-differences in prostaglandin signaling: a semi-systematic review and characterization of PTGDS expression in human sensory neurons
por: Shen, Breanna Q., et al.
Publicado: (2023)

Sirt6 promotes tumorigenesis and drug resistance of diffuse large B-cell lymphoma by mediating PI3K/Akt signaling
por: Yang, Juan, et al.
Publicado: (2020)

Knockdown of LncRNA CRNDE suppresses proliferation and P-glycoprotein-mediated multidrug resistance in acute myelocytic leukemia through the Wnt/β-catenin pathway
por: Kang, Yiqing, et al.
Publicado: (2020)

TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/β-catenin pathway
por: Zhu, Linan, et al.
Publicado: (2018)

Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
por: Nguyen, Vu Hong Loan, et al.
Publicado: (2019)

Nuclear partitioning of Prohibitin 1 inhibits Wnt/β-catenin-dependent intestinal tumorigenesis
por: Alula, Kibrom M., et al.
Publicado: (2020)

Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway
por: Wang, Zuoyun, et al.
Publicado: (2020)

Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma
por: Zhou, Xiangxiang, et al.
Publicado: (2020)

ER-depletion lowering the 'hypothalamus-uterus-kidney' axis functions by perturbing the renal ERβ/Ptgds signalling pathway
por: Liu, Yan-Ru, et al.
Publicado: (2019)

Nonmuscle myosin 2 proteins encoded by Myh9, Myh10, and Myh14 are uniquely distributed in the tubular segments of murine kidney
por: Otterpohl, Karla L., et al.
Publicado: (2017)

Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis
por: Oshima, Hiroko, et al.
Publicado: (2019)

PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis
por: Tang, Yuling, et al.
Publicado: (2022)

FAM84B, amplified in pancreatic ductal adenocarcinoma, promotes tumorigenesis through the Wnt/β-catenin pathway
por: Zhang, Xin, et al.
Publicado: (2020)

PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway
por: Zhan, Ping, et al.
Publicado: (2017)

HOXB4 inhibits the proliferation and tumorigenesis of cervical cancer cells by downregulating the activity of Wnt/β-catenin signaling pathway
por: Lei, Dan, et al.
Publicado: (2021)

SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis
por: Fu, Yu, et al.
Publicado: (2013)

RBM5 inhibits tumorigenesis of gliomas through inhibition of Wnt/β-catenin signaling and induction of apoptosis
por: Jiang, Yuanpei, et al.
Publicado: (2017)

Cell–cell adhesion: linking Wnt/β-catenin signaling with partial EMT and stemness traits in tumorigenesis
por: Basu, Sayon, et al.
Publicado: (2018)

circ_0003418 Inhibits Tumorigenesis And Cisplatin Chemoresistance Through Wnt/β-Catenin Pathway In Hepatocellular Carcinoma
por: Chen, Hang, et al.
Publicado: (2019)

ANDROGEN RECEPTOR WITH SHORT POLYGLUTAMINE TRACT PREFERABLY ENHANCES WNT/β-CATENIN MEDIATED PROSTATIC TUMORIGENESIS
por: He, Yongfeng, et al.
Publicado: (2020)

Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2
por: Hao, Jiaxue, et al.
Publicado: (2021)

ZNRF3 Inhibits the Invasion and Tumorigenesis in Nasopharyngeal Carcinoma Cells by Inactivating the Wnt/β-Catenin Pathway
por: Wang, Zhongwei, et al.
Publicado: (2017)

Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation
por: Zou, Ruoyao, et al.
Publicado: (2020)

β-catenin in epithelial tumorigenesis
por: Lu, Tsai-Ling, et al.
Publicado: (2015)

Myosin Heavy Chain 10 (MYH10) Gene Silencing Reduces Cell Migration and Invasion in the Glioma Cell Lines U251, T98G, and SHG44 by Inhibiting the Wnt/β-Catenin Pathway
por: Wang, Yang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9iol0h91ue705bsr7cik52absn