EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation

BACKGROUND: Diabetic nephropathy (DN) is characterized by albuminuria and accumulation of extracellular matrix (ECM) in kidney. Transforming growth factor-β (TGF-β) plays a central role in promoting ECM accumulation. We aimed to examine the effects of EW-7197, an inhibitor of TGF-β type 1 receptor k...

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Detalles Bibliográficos
Autores principales: Ha, Kyung Bong, Sangartit, Weerapon, Jeong, Ah Reum, Lee, Eun Soo, Kim, Hong Min, Shim, Soyeon, Kukongviriyapan, Upa, Kim, Dae-Kee, Lee, Eun Young, Chung, Choon Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901963/
https://www.ncbi.nlm.nih.gov/pubmed/35255604
http://dx.doi.org/10.3803/EnM.2021.1305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901963/
https://www.ncbi.nlm.nih.gov/pubmed/35255604
http://dx.doi.org/10.3803/EnM.2021.1305

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