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EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation

BACKGROUND: Diabetic nephropathy (DN) is characterized by albuminuria and accumulation of extracellular matrix (ECM) in kidney. Transforming growth factor-β (TGF-β) plays a central role in promoting ECM accumulation. We aimed to examine the effects of EW-7197, an inhibitor of TGF-β type 1 receptor k...

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Detalles Bibliográficos
Autores principales:	Ha, Kyung Bong, Sangartit, Weerapon, Jeong, Ah Reum, Lee, Eun Soo, Kim, Hong Min, Shim, Soyeon, Kukongviriyapan, Upa, Kim, Dae-Kee, Lee, Eun Young, Chung, Choon Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901963/ https://www.ncbi.nlm.nih.gov/pubmed/35255604 http://dx.doi.org/10.3803/EnM.2021.1305

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