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Succinate/IL-1β Signaling Axis Promotes the Inflammatory Progression of Endothelial and Exacerbates Atherosclerosis

Inflammation is an important driver of atherosclerosis. Succinate is a new extracellular inflammatory alarm released by activated macrophages. Succinate is sensed by succinate receptor 1 (Sucnr1) and then transferred to effector cells. It is worth exploring whether succinate is capable of facilitati...

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Detalles Bibliográficos
Autores principales: Xu, Jingwen, Zheng, Yabing, Zhao, Yaqing, Zhang, Yujiao, Li, Huilin, Zhang, An, Wang, Xuehan, Wang, Weizong, Hou, Yinglong, Wang, Jiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901997/
https://www.ncbi.nlm.nih.gov/pubmed/35273600
http://dx.doi.org/10.3389/fimmu.2022.817572

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