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Succinate/IL-1β Signaling Axis Promotes the Inflammatory Progression of Endothelial and Exacerbates Atherosclerosis
Inflammation is an important driver of atherosclerosis. Succinate is a new extracellular inflammatory alarm released by activated macrophages. Succinate is sensed by succinate receptor 1 (Sucnr1) and then transferred to effector cells. It is worth exploring whether succinate is capable of facilitati...
Autores principales: | Xu, Jingwen, Zheng, Yabing, Zhao, Yaqing, Zhang, Yujiao, Li, Huilin, Zhang, An, Wang, Xuehan, Wang, Weizong, Hou, Yinglong, Wang, Jiangrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901997/ https://www.ncbi.nlm.nih.gov/pubmed/35273600 http://dx.doi.org/10.3389/fimmu.2022.817572 |
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