Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective

The coronavirus disease 2019 (COVID-19) vaccines have very successfully decreased the disease risk as we know; some key information remains unknown due to the short development history and the lack of long-term follow-up studies in vaccinated populations. One of the unanswered issues is the protecti...

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Detalles Bibliográficos
Autores principales: Zhuang, Chunlan, Liu, Xiaohui, Chen, Qi, Sun, Yuxin, Su, Yingying, Huang, Shoujie, Wu, Ting, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902038/
https://www.ncbi.nlm.nih.gov/pubmed/35273584
http://dx.doi.org/10.3389/fmicb.2022.828806
Descripción
Sumario:The coronavirus disease 2019 (COVID-19) vaccines have very successfully decreased the disease risk as we know; some key information remains unknown due to the short development history and the lack of long-term follow-up studies in vaccinated populations. One of the unanswered issues is the protection duration conferred after COVID-19 vaccination, which appears to play a pivotal role in the future impact of pathogens and is critical to inform the public health response and policy decisions. Here, we review current information on the long-term effectiveness of different COVID-19 vaccines, persistence of immunogenicity, and gaps in knowledge. Meanwhile, we also discuss the influencing factors and future study prospects on this topic.

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