Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective

The coronavirus disease 2019 (COVID-19) vaccines have very successfully decreased the disease risk as we know; some key information remains unknown due to the short development history and the lack of long-term follow-up studies in vaccinated populations. One of the unanswered issues is the protecti...

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Autores principales: Zhuang, Chunlan, Liu, Xiaohui, Chen, Qi, Sun, Yuxin, Su, Yingying, Huang, Shoujie, Wu, Ting, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902038/
https://www.ncbi.nlm.nih.gov/pubmed/35273584
http://dx.doi.org/10.3389/fmicb.2022.828806
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author Zhuang, Chunlan
Liu, Xiaohui
Chen, Qi
Sun, Yuxin
Su, Yingying
Huang, Shoujie
Wu, Ting
Xia, Ningshao
author_facet Zhuang, Chunlan
Liu, Xiaohui
Chen, Qi
Sun, Yuxin
Su, Yingying
Huang, Shoujie
Wu, Ting
Xia, Ningshao
author_sort Zhuang, Chunlan
collection PubMed
description The coronavirus disease 2019 (COVID-19) vaccines have very successfully decreased the disease risk as we know; some key information remains unknown due to the short development history and the lack of long-term follow-up studies in vaccinated populations. One of the unanswered issues is the protection duration conferred after COVID-19 vaccination, which appears to play a pivotal role in the future impact of pathogens and is critical to inform the public health response and policy decisions. Here, we review current information on the long-term effectiveness of different COVID-19 vaccines, persistence of immunogenicity, and gaps in knowledge. Meanwhile, we also discuss the influencing factors and future study prospects on this topic.
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spelling pubmed-89020382022-03-09 Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective Zhuang, Chunlan Liu, Xiaohui Chen, Qi Sun, Yuxin Su, Yingying Huang, Shoujie Wu, Ting Xia, Ningshao Front Microbiol Microbiology The coronavirus disease 2019 (COVID-19) vaccines have very successfully decreased the disease risk as we know; some key information remains unknown due to the short development history and the lack of long-term follow-up studies in vaccinated populations. One of the unanswered issues is the protection duration conferred after COVID-19 vaccination, which appears to play a pivotal role in the future impact of pathogens and is critical to inform the public health response and policy decisions. Here, we review current information on the long-term effectiveness of different COVID-19 vaccines, persistence of immunogenicity, and gaps in knowledge. Meanwhile, we also discuss the influencing factors and future study prospects on this topic. Frontiers Media S.A. 2022-02-22 /pmc/articles/PMC8902038/ /pubmed/35273584 http://dx.doi.org/10.3389/fmicb.2022.828806 Text en Copyright © 2022 Zhuang, Liu, Chen, Sun, Su, Huang, Wu and Xia. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Zhuang, Chunlan
Liu, Xiaohui
Chen, Qi
Sun, Yuxin
Su, Yingying
Huang, Shoujie
Wu, Ting
Xia, Ningshao
Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title_full Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title_fullStr Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title_full_unstemmed Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title_short Protection Duration of COVID-19 Vaccines: Waning Effectiveness and Future Perspective
title_sort protection duration of covid-19 vaccines: waning effectiveness and future perspective
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902038/
https://www.ncbi.nlm.nih.gov/pubmed/35273584
http://dx.doi.org/10.3389/fmicb.2022.828806
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