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IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy

Orbital fibrosis is a hallmark of tissue remodeling in thyroid-associated ophthalmopathy (TAO). Previous studies have shown that interleukin (IL)-11 plays a pivotal profibrotic role in various inflammatory and autoimmune diseases. However, the expression pattern of IL-11 in patients with TAO and whe...

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Detalles Bibliográficos
Autores principales: Wu, Pengsen, Lin, Bingying, Huang, Siyu, Meng, Jie, Zhang, Fan, Zhou, Min, Hei, Xiangqing, Ke, Yu, Yang, Huasheng, Huang, Danping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902078/
https://www.ncbi.nlm.nih.gov/pubmed/35273577
http://dx.doi.org/10.3389/fendo.2022.846106

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