Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies

BACKGROUND: Chimeric antigen receptor (CAR) T cells directed against CD19 (CART19) are effective in B-cell malignancies, but little is known about the molecular factors predicting clinical outcome of CART19 therapy. The increasingly recognized relevance of epigenetic changes in cancer immunology pro...

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Detalles Bibliográficos
Autores principales: Garcia-Prieto, Carlos A, Villanueva, Lorea, Bueno-Costa, Alberto, Davalos, Veronica, González-Navarro, Europa Azucena, Juan, Manel, Urbano-Ispizua, Álvaro, Delgado, Julio, Ortiz-Maldonado, Valentín, del Bufalo, Francesca, Locatelli, Franco, Quintarelli, Concetta, Sinibaldi, Matilde, Soler, Marta, Castro de Moura, Manuel, Ferrer, Gerardo, Urdinguio, Rocio G, Fernandez, Agustin F, Fraga, Mario F, Bar, Diana, Meir, Amilia, Itzhaki, Orit, Besser, Michal J, Avigdor, Abraham, Jacoby, Elad, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902331/
https://www.ncbi.nlm.nih.gov/pubmed/34581788
http://dx.doi.org/10.1093/jnci/djab194

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