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Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice

BACKGROUND: Aging is one of the most important risk factors of postoperative cognitive dysfunction (POCD); however, the mechanisms are still not completely understood. In this study, we explore the roles of matrix metalloproteinase-9 (MMP-9) in aged mice with POCD. METHODS: Appendectomy was performe...

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Detalles Bibliográficos
Autores principales: Huang, Lili, Tian, Weitian, Chen, Xuemei, Xu, Huan, Dai, Wanbing, Zhang, Yizhe, Wu, Xiaodan, Yu, Weifeng, Tian, Jie, Su, Diansan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902411/
https://www.ncbi.nlm.nih.gov/pubmed/35273488
http://dx.doi.org/10.3389/fnagi.2022.683295