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mt tRFs, New Players in MELAS Disease

MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) is an OXPHOS disease mostly caused by the m.3243A>G mutation in the mitochondrial tRNA(Leu(UUR)) gene. Recently, we have shown that the mutation significantly changes the expression pattern of several mitochondrial...

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Detalles Bibliográficos
Autores principales: Meseguer, Salvador, Rubio, Mari-Paz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902416/
https://www.ncbi.nlm.nih.gov/pubmed/35273517
http://dx.doi.org/10.3389/fphys.2022.800171