Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1(G93A) Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons

Sex steroid hormones have been implicated as disease modifiers in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS). Androgens, signalling via the androgen receptor (AR), predominate in males, and have widespread actions in the periphery and the central nervous system (CNS). AR tran...

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Detalles Bibliográficos
Autores principales: McLeod, Victoria M., Chiam, Mathew D. F., Perera, Nirma D., Lau, Chew L., Boon, Wah Chin, Turner, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902593/
https://www.ncbi.nlm.nih.gov/pubmed/35273564
http://dx.doi.org/10.3389/fendo.2022.808479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902593/
https://www.ncbi.nlm.nih.gov/pubmed/35273564
http://dx.doi.org/10.3389/fendo.2022.808479

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