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Vascular hyperacetylation is associated with vascular smooth muscle dysfunction in a rat model of non-obese type 2 diabetes

BACKGROUND: Advanced type 2 diabetes mellitus (T2DM) accelerates vascular smooth muscle cell (VSMC) dysfunction which contributes to the development of vasculopathy, associated with the highest degree of morbidity of T2DM. Lysine acetylation, a post-translational modification (PTM), has been associa...

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Detalles Bibliográficos
Autores principales: Carrillo-Sepulveda, Maria Alicia, Maddie, Nicole, Johnson, Christina Mary, Burke, Cameron, Lutz, Osina, Yakoub, Bamwa, Kramer, Benjamin, Persand, Dhandevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902773/
https://www.ncbi.nlm.nih.gov/pubmed/35260080
http://dx.doi.org/10.1186/s10020-022-00441-4