Cargando…
Identification of chromatin loops from Hi-C interaction matrices by CTCF–CTCF topology classification
Genome-wide profiling of long-range interactions has revealed that the CCCTC-Binding factor (CTCF) often anchors chromatin loops and is enriched at boundaries of the so-called Topologically Associating Domains, which suggests that CTCF is essential in the 3D organization of chromatin. However, the s...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903010/ https://www.ncbi.nlm.nih.gov/pubmed/35274099 http://dx.doi.org/10.1093/nargab/lqac021 |