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Identification of chromatin loops from Hi-C interaction matrices by CTCF–CTCF topology classification

Genome-wide profiling of long-range interactions has revealed that the CCCTC-Binding factor (CTCF) often anchors chromatin loops and is enriched at boundaries of the so-called Topologically Associating Domains, which suggests that CTCF is essential in the 3D organization of chromatin. However, the s...

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Detalles Bibliográficos
Autores principales: Galan, Silvia, Serra, François, Marti-Renom, Marc A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903010/
https://www.ncbi.nlm.nih.gov/pubmed/35274099
http://dx.doi.org/10.1093/nargab/lqac021