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Identification of chromatin loops from Hi-C interaction matrices by CTCF–CTCF topology classification
Genome-wide profiling of long-range interactions has revealed that the CCCTC-Binding factor (CTCF) often anchors chromatin loops and is enriched at boundaries of the so-called Topologically Associating Domains, which suggests that CTCF is essential in the 3D organization of chromatin. However, the s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903010/ https://www.ncbi.nlm.nih.gov/pubmed/35274099 http://dx.doi.org/10.1093/nargab/lqac021 |