A comprehensive atlas of fetal splicing patterns in the brain of adult myotonic dystrophy type 1 patients

In patients with myotonic dystrophy type 1 (DM1), dysregulation of RNA-binding proteins like MBNL and CELF1 leads to alternative splicing of exons and is thought to induce a return to fetal splicing patterns in adult tissues, including the central nervous system (CNS). To comprehensively evaluate th...

Descripción completa

Detalles Bibliográficos
Autores principales: Degener, Max J F, van Cruchten, Remco T P, Otero, Brittney A, Wang, Eric T, Wansink, Derick G, ‘t Hoen, Peter A C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903011/
https://www.ncbi.nlm.nih.gov/pubmed/35274098
http://dx.doi.org/10.1093/nargab/lqac016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903011/
https://www.ncbi.nlm.nih.gov/pubmed/35274098
http://dx.doi.org/10.1093/nargab/lqac016

Ejemplares similares