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A comprehensive atlas of fetal splicing patterns in the brain of adult myotonic dystrophy type 1 patients

In patients with myotonic dystrophy type 1 (DM1), dysregulation of RNA-binding proteins like MBNL and CELF1 leads to alternative splicing of exons and is thought to induce a return to fetal splicing patterns in adult tissues, including the central nervous system (CNS). To comprehensively evaluate th...

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Detalles Bibliográficos
Autores principales:	Degener, Max J F, van Cruchten, Remco T P, Otero, Brittney A, Wang, Eric T, Wansink, Derick G, ‘t Hoen, Peter A C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Standard Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903011/ https://www.ncbi.nlm.nih.gov/pubmed/35274098 http://dx.doi.org/10.1093/nargab/lqac016

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