XAF1 directs glioma response to temozolomide through apoptotic transition of autophagy by activation of ATM–AMPK signaling

BACKGROUND: X-linked inhibitor of apoptosis-associated factor 1 (XAF1) is a tumor suppressor that is commonly inactivated in multiple human cancers. However, its role in the pathogenesis and therapeutic response of glioma is poorly characterized. METHODS: XAF1 activation by temozolomide (TMZ) and it...

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Detalles Bibliográficos
Autores principales: Lee, Min-Goo, Choi, Zisun, Lim, Na-Jung, Lim, Ji-Sun, Lee, Kyung-Woo, Ko, Kyung-Phil, Ryu, Byung-Kyu, Kang, Shin-Hyuk, Chi, Sung-Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903238/
https://www.ncbi.nlm.nih.gov/pubmed/35274103
http://dx.doi.org/10.1093/noajnl/vdac013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903238/
https://www.ncbi.nlm.nih.gov/pubmed/35274103
http://dx.doi.org/10.1093/noajnl/vdac013

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