Cargando…

The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections

The Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND) began development of a broad-spectrum antiviral countermeasure against deliberate use of high-consequence viral hemorrhagic fevers (VHFs) in 2016. The effort featured comprehensive preclinical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hickman, Mark R., Saunders, David L., Bigger, Catherine A., Kane, Christopher D., Iversen, Patrick L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903284/ https://www.ncbi.nlm.nih.gov/pubmed/35259154 http://dx.doi.org/10.1371/journal.pntd.0010220

Ejemplares similares

Autophagy, antiviral immunity, and viral countermeasures
por: Shoji-Kawata, Sanae, et al.
Publicado: (2009)

Hemorrhagic Fever Viruses: Pathogenesis and Countermeasures
por: Mire, Chad E., et al.
Publicado: (2022)

Broad-spectrum antivirals against viral fusion
por: Vigant, Frederic, et al.
Publicado: (2015)

Activation of the Antiviral Kinase PKR and Viral Countermeasures
por: Dauber, Bianca, et al.
Publicado: (2009)

Preparing for the next viral threat with broad-spectrum antivirals
por: Karim, Marwah, et al.
Publicado: (2023)

Broad-Spectrum Antivirals Derived from Natural Products
por: Tian, Wen-Jun, et al.
Publicado: (2023)

Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
por: Mazzon, Michela, et al.
Publicado: (2019)

Targeting viral entry as a strategy for broad-spectrum antivirals
por: Mazzon, Michela, et al.
Publicado: (2019)

Broad-Spectrum Antiviral Therapeutics
por: Rider, Todd H., et al.
Publicado: (2011)

A Potent, Broad-Spectrum Antiviral Agent that Targets Viral Membranes
por: Wojcechowskyj, Jason A., et al.
Publicado: (2010)

Broad-spectrum antiviral agents
por: Zhu, Jun-Da, et al.
Publicado: (2015)

Broad-Spectrum Antivirals and Antiviral Drug Combinations
por: Oksenych, Valentyn, et al.
Publicado: (2022)

Broad-Spectrum Antivirals and Antiviral Combinations: An Editorial Update
por: Kainov, Denis, et al.
Publicado: (2022)

Toxins as biological weapons for terror—characteristics, challenges and medical countermeasures: a mini-review
por: Berger, Tamar, et al.
Publicado: (2016)

Modified cyclodextrins as broad-spectrum antivirals
por: Jones, Samuel T., et al.
Publicado: (2020)

Development of Broad-Spectrum Antiviral Agents—Inspiration from Immunomodulatory Natural Products
por: Zhang, Mengxun, et al.
Publicado: (2021)

Broad Spectrum Antiviral Activity of Favipiravir (T-705): Protection from Highly Lethal Inhalational Rift Valley Fever
por: Caroline, Amy L., et al.
Publicado: (2014)

Arbidol as a broad-spectrum antiviral: An update
por: Blaising, Julie, et al.
Publicado: (2014)

Broad-Spectrum Antiviral Strategies and Nucleoside Analogues
por: Geraghty, Robert J., et al.
Publicado: (2021)

dsRNA as broad-spectrum antiviral therapeutics
por: Xu, Congfei
Publicado: (2022)

Interferon, Mx, and viral countermeasures
por: Haller, Otto, et al.
Publicado: (2007)

A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope
por: Luteijn, Rutger D., et al.
Publicado: (2020)

Viral polymerase binding and broad-spectrum antiviral activity of molnupiravir against human seasonal coronaviruses
por: Wang, Yining, et al.
Publicado: (2021)

Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies
por: Soto-Acosta, Ruben, et al.
Publicado: (2021)

Immunoglobulin M: An Ancient Antiviral Weapon – Rediscovered
por: Gong, Siqi, et al.
Publicado: (2020)

Broad spectrum antiviral nucleosides—Our best hope for the future
por: Seley-Radtke, Katherine L., et al.
Publicado: (2021)

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
por: Goodier, John L., et al.
Publicado: (2015)

Antimicrobial Peptides and Cationic Nanoparticles: A Broad-Spectrum Weapon to Fight Multi-Drug Resistance Not Only in Bacteria
por: Valenti, Giulia E., et al.
Publicado: (2022)

The broad-spectrum antiviral functions of IFIT and IFITM proteins
por: Diamond, Michael S., et al.
Publicado: (2012)

Drug repurposing for new, efficient, broad spectrum antivirals
por: García-Serradilla, Moisés, et al.
Publicado: (2019)

Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses
por: Ekins, Sean, et al.
Publicado: (2020)

Conserved coronavirus proteins as targets of broad-spectrum antivirals
por: Melo-Filho, Cleber C., et al.
Publicado: (2022)

Near-Infrared Dyes: Towards Broad-Spectrum Antivirals
por: Mariewskaya, Kseniya A., et al.
Publicado: (2022)

MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation
por: Lin, Ren-Jye, et al.
Publicado: (2013)

Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes
por: Levi, Laura I., et al.
Publicado: (2021)

Broad-Spectrum Antibiotic or G-CSF as Potential Countermeasures for Impaired Control of Bacterial Infection Associated with an SPE Exposure during Spaceflight
por: Li, Minghong, et al.
Publicado: (2015)

Viral Hemorrhagic Fever Preparedness
por: Hewlett, Angela, et al.
Publicado: (2017)

Broad-Spectrum Antiviral Natural Products from the Marine-Derived Penicillium sp. IMB17-046
por: Li, Jiao, et al.
Publicado: (2019)

In-Silico Approaches for the Screening and Discovery of Broad-Spectrum Marine Natural Product Antiviral Agents Against Coronaviruses
por: Boswell, Zachary, et al.
Publicado: (2023)

Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine
por: De Clercq, Erik, et al.
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_u9rbf6icg4816paouvv53na0ii