Cargando…
Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study
Coronavirus disease 2019 symptom definitions rarely include symptom severity. We collected daily nasal swab samples and symptom diaries from contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case patients. Requiring ≥1 moderate or severe symptom reduced sensitivity to predict...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903379/ https://www.ncbi.nlm.nih.gov/pubmed/35152299 http://dx.doi.org/10.1093/cid/ciac129 |
| _version_ | 1784664739075325952 |
|---|---|
| author | Bershteyn, Anna Dahl, Angela M Dong, Tracy Q Deming, Meagan E Celum, Connie L Chu, Helen Y Kottkamp, Angelica C Greninger, Alexander L Hoffman, Risa M Jerome, Keith R Johnston, Christine M Kissinger, Patricia J Landovitz, Raphael J Laufer, Miriam K Luk, Alfred Neuzil, Kathleen M Paasche-Orlow, Michael K Pitts, Robert A Schwartz, Mark D Stankiewicz Karita, Helen C Thorpe, Lorna E Wald, Anna Zheng, Crystal Y Wener, Mark H Barnabas, Ruanne V Brown, Elizabeth R |
| author_facet | Bershteyn, Anna Dahl, Angela M Dong, Tracy Q Deming, Meagan E Celum, Connie L Chu, Helen Y Kottkamp, Angelica C Greninger, Alexander L Hoffman, Risa M Jerome, Keith R Johnston, Christine M Kissinger, Patricia J Landovitz, Raphael J Laufer, Miriam K Luk, Alfred Neuzil, Kathleen M Paasche-Orlow, Michael K Pitts, Robert A Schwartz, Mark D Stankiewicz Karita, Helen C Thorpe, Lorna E Wald, Anna Zheng, Crystal Y Wener, Mark H Barnabas, Ruanne V Brown, Elizabeth R |
| author_sort | Bershteyn, Anna |
| collection | PubMed |
| description | Coronavirus disease 2019 symptom definitions rarely include symptom severity. We collected daily nasal swab samples and symptom diaries from contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case patients. Requiring ≥1 moderate or severe symptom reduced sensitivity to predict SARS-CoV-2 shedding from 60.0% (95% confidence interval [CI], 52.9%−66.7%) to 31.5% (95% CI, 25.7%− 38.0%) but increased specificity from 77.5% (95% CI, 75.3%−79.5%) to 93.8% (95% CI, 92.7%−94.8%). |
| format | Online Article Text |
| id | pubmed-8903379 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-89033792022-03-09 Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study Bershteyn, Anna Dahl, Angela M Dong, Tracy Q Deming, Meagan E Celum, Connie L Chu, Helen Y Kottkamp, Angelica C Greninger, Alexander L Hoffman, Risa M Jerome, Keith R Johnston, Christine M Kissinger, Patricia J Landovitz, Raphael J Laufer, Miriam K Luk, Alfred Neuzil, Kathleen M Paasche-Orlow, Michael K Pitts, Robert A Schwartz, Mark D Stankiewicz Karita, Helen C Thorpe, Lorna E Wald, Anna Zheng, Crystal Y Wener, Mark H Barnabas, Ruanne V Brown, Elizabeth R Clin Infect Dis Brief Report Coronavirus disease 2019 symptom definitions rarely include symptom severity. We collected daily nasal swab samples and symptom diaries from contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case patients. Requiring ≥1 moderate or severe symptom reduced sensitivity to predict SARS-CoV-2 shedding from 60.0% (95% confidence interval [CI], 52.9%−66.7%) to 31.5% (95% CI, 25.7%− 38.0%) but increased specificity from 77.5% (95% CI, 75.3%−79.5%) to 93.8% (95% CI, 92.7%−94.8%). Oxford University Press 2022-02-13 /pmc/articles/PMC8903379/ /pubmed/35152299 http://dx.doi.org/10.1093/cid/ciac129 Text en © The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Brief Report Bershteyn, Anna Dahl, Angela M Dong, Tracy Q Deming, Meagan E Celum, Connie L Chu, Helen Y Kottkamp, Angelica C Greninger, Alexander L Hoffman, Risa M Jerome, Keith R Johnston, Christine M Kissinger, Patricia J Landovitz, Raphael J Laufer, Miriam K Luk, Alfred Neuzil, Kathleen M Paasche-Orlow, Michael K Pitts, Robert A Schwartz, Mark D Stankiewicz Karita, Helen C Thorpe, Lorna E Wald, Anna Zheng, Crystal Y Wener, Mark H Barnabas, Ruanne V Brown, Elizabeth R Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title | Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title_full | Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title_fullStr | Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title_full_unstemmed | Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title_short | Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study |
| title_sort | self-assessed severity as a determinant of coronavirus disease 2019 symptom specificity: a longitudinal cohort study |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903379/ https://www.ncbi.nlm.nih.gov/pubmed/35152299 http://dx.doi.org/10.1093/cid/ciac129 |
| work_keys_str_mv | AT bershteynanna selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT dahlangelam selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT dongtracyq selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT demingmeagane selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT celumconniel selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT chuheleny selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT kottkampangelicac selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT greningeralexanderl selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT hoffmanrisam selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT jeromekeithr selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT johnstonchristinem selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT kissingerpatriciaj selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT landovitzraphaelj selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT laufermiriamk selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT lukalfred selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT neuzilkathleenm selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT paascheorlowmichaelk selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT pittsroberta selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT schwartzmarkd selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT stankiewiczkaritahelenc selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT thorpelornae selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT waldanna selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT zhengcrystaly selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT wenermarkh selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT barnabasruannev selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy AT brownelizabethr selfassessedseverityasadeterminantofcoronavirusdisease2019symptomspecificityalongitudinalcohortstudy |