Cargando…

IL-17 crosses the blood–brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine

BACKGROUND: Chronic migraine places a disabling burden on patients, which is extensively modeled by the nitroglycerin (NTG)-treated animal model. Although the NF-κB pathway is involved in an increase in CGRP levels and activation of the trigeminal system in the NTG model, the relationship between NT...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hao, Tang, Xueqian, Li, Jin, Hu, Bangyan, Yang, Wenqin, Zhan, Meng, Ma, Tengyun, Xu, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903553/
https://www.ncbi.nlm.nih.gov/pubmed/34979902
http://dx.doi.org/10.1186/s10194-021-01374-9