Calcitonin gene-related peptide receptor antagonist BIBN4096BS regulates synaptic transmission in the vestibular nucleus and improves vestibular function via PKC/ERK/CREB pathway in an experimental chronic migraine rat model

BACKGROUND: Vestibular symptoms are frequently reported in patients with chronic migraine (CM). However, whether vestibular symptoms arise through overlapping neurobiology of migraine remains to be elucidated. The neuropeptide calcitonin gene-related peptide (CGRP) and CGRP1 receptor play important...

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Detalles Bibliográficos
Autores principales: Tian, Ruimin, Zhang, Yun, Pan, Qi, Wang, Yunfeng, Wen, Qianwen, Fan, Xiaoping, Qin, Guangcheng, Zhang, Dunke, Chen, Lixue, Zhang, Yixin, Zhou, Jiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903578/
https://www.ncbi.nlm.nih.gov/pubmed/35260079
http://dx.doi.org/10.1186/s10194-022-01403-1

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