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Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation

BACKGROUND: Purinergic P2X7 receptor plays an important role in migraine pathophysiology. Yet precise molecular mechanism underlying P2X7R signaling in migraine remains unclear. This study explores the hypothesis that P2X7 receptor transmits signaling to Src family kinases (SFKs) during cortical spr...

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Detalles Bibliográficos
Autores principales: Nie, Lingdi, Ma, Dongqing, Quinn, John P., Wang, Minyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903689/
https://www.ncbi.nlm.nih.gov/pubmed/34863113
http://dx.doi.org/10.1186/s10194-021-01359-8

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