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Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice

BACKGROUND: Postoperative cognitive dysfunction (POCD) is a common complication following anesthesia and surgery. General anesthetic isoflurane has potential neurotoxicity and induces cognitive impairments, but the exact mechanism remains unclear. Astrocytes form interconnected networks in the adult...

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Detalles Bibliográficos
Autores principales:	Dong, Rui, Han, Yuqiang, Jiang, Linhao, Liu, Shuai, Zhang, Fujun, Peng, Liangyu, Wang, Zimo, Ma, Zhengliang, Xia, Tianjiao, Gu, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903726/ https://www.ncbi.nlm.nih.gov/pubmed/35255943 http://dx.doi.org/10.1186/s12974-022-02424-y

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