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Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model
Background: Previous studies have proven that Purinostat Mesylate (PM) is a new HDAC inhibitor and exhibits significant antitumor efficacy. However, the clinical application of PM was greatly limited by its poor solubility in water and low bioavailability. Objective:To increase the solubility of PM...
Autores principales: | Zhu, Zejiang, Wen, Jiaolin, Xu, Yaohui, Pei, Heying, Li, Dan, Tang, Minghai, Bai, Peng, He, Jun, Yang, Zhuang, Chen, Lijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903780/ https://www.ncbi.nlm.nih.gov/pubmed/35243950 http://dx.doi.org/10.1080/07853890.2022.2045347 |
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