Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 trial

BACKGROUND: Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based recombinant Newcastle disease virus vaccine expressing the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS...

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Autores principales: Pitisuttithum, Punnee, Luvira, Viravarn, Lawpoolsri, Saranath, Muangnoicharoen, Sant, Kamolratanakul, Supitcha, Sivakorn, Chaisith, Narakorn, Piengthong, Surichan, Somchaiya, Prangpratanporn, Sumalee, Puksuriwong, Suttida, Lamola, Steven, Mercer, Laina D., Raghunandan, Rama, Sun, Weina, Liu, Yonghong, Carreño, Juan Manuel, Scharf, Rami, Phumratanaprapin, Weerapong, Amanat, Fatima, Gagnon, Luc, Hsieh, Ching-Lin, Kaweepornpoj, Ruangchai, Khan, Sarwat, Lal, Manjari, McCroskery, Stephen, McLellan, Jason, Mena, Ignacio, Meseck, Marcia, Phonrat, Benjaluck, Sabmee, Yupa, Singchareon, Ratsamikorn, Slamanig, Stefan, Suthepakul, Nava, Tcheou, Johnstone, Thantamnu, Narumon, Theerasurakarn, Sompone, Tran, Steven, Vilasmongkolchai, Thanakrit, White, Jessica A, Bhardwaj, Nina, Garcia-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Poopipatpol, Kittisak, Wirachwong, Ponthip, Hjorth, Richard, Innis, Bruce L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903824/
https://www.ncbi.nlm.nih.gov/pubmed/35284808
http://dx.doi.org/10.1016/j.eclinm.2022.101323

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