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Inhibition of SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity

Natural killer (NK) cells play a crucial role in immunity, killing virally infected and cancerous cells. The balance of signals initiated upon engagement of activating and inhibitory NK receptors with cognate ligands determines killing or tolerance. Nevertheless, the molecular mechanisms regulating...

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Detalles Bibliográficos
Autores principales:	Ben-Shmuel, Aviad, Sabag, Batel, Puthenveetil, Abhishek, Biber, Guy, Levy, Moria, Jubany, Tammir, Awwad, Fatima, Roy, Roshan Kumar, Joseph, Noah, Matalon, Omri, Kivelevitz, Jessica, Barda-Saad, Mira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903836/ https://www.ncbi.nlm.nih.gov/pubmed/35258455 http://dx.doi.org/10.7554/eLife.73282

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