Fluid shear stress enhances T cell activation through Piezo1

BACKGROUND: T cell activation is a mechanical process as much as it is a biochemical process. In this study, we used a cone-and-plate viscometer system to treat Jurkat and primary human T cells with fluid shear stress (FSS) to enhance the activation of the T cells through mechanical means. RESULTS:...

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Detalles Bibliográficos
Autores principales: Hope, Jacob M., Dombroski, Jenna A., Pereles, Rebecca S., Lopez-Cavestany, Maria, Greenlee, Joshua D., Schwager, Samantha C., Reinhart-King, Cynthia A., King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904069/
https://www.ncbi.nlm.nih.gov/pubmed/35260156
http://dx.doi.org/10.1186/s12915-022-01266-7

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