Active immunization with a Her-2/neu-targeting Multi-peptide B cell vaccine prevents lung metastases formation from Her-2/neu breast cancer in a mouse model

In pre-clinical and clinical settings, active immunization with a Her-2/neu vaccine (HerVaxx), comprising B-cell peptide from Trastuzumab binding site, has been shown to reduce primary tumor growth via induction of polyclonal anti-tumor immune responses and immunological memory. Here, we tested the...

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Detalles Bibliográficos
Autores principales: Tobias, Joshua, Drinić, Mirjana, Högler, Sandra, Ambroz, Katharina, Baier, Karin, Kodajova, Petra, Tomasich, Erwin, Berghoff, Anna S., Schmid, Anna, Garner-Spitzer, Erika, Kenner, Lukas, Kundi, Michael, Zielinski, Christoph C., Wiedermann, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904231/
https://www.ncbi.nlm.nih.gov/pubmed/35259675
http://dx.doi.org/10.1016/j.tranon.2022.101378

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