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A NanoBiT assay to monitor membrane proteins trafficking for drug discovery and drug development
Internalization of membrane proteins plays a key role in many physiological functions; however, highly sensitive and versatile technologies are lacking to study such processes in real-time living systems. Here we describe an assay based on bioluminescence able to quantify membrane receptor trafficki...
Autores principales: | Reyes-Alcaraz, Arfaxad, Lucero Garcia-Rojas, Emilio Y., Merlinsky, Elizabeth A., Seong, Jae Young, Bond, Richard A., McConnell, Bradley K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904512/ https://www.ncbi.nlm.nih.gov/pubmed/35260793 http://dx.doi.org/10.1038/s42003-022-03163-9 |
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