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Discovery of antimicrobials by massively parallelized growth assays (Me(x))
The number of newly approved antimicrobial compounds has been steadily decreasing over the past 50 years emphasizing the need for novel antimicrobial substances. Here we present Me(x), a method for the high-throughput discovery of novel antimicrobials, that relies on E. coli self-screening to determ...
Autores principales: | Koch, Philipp, Schmitt, Steven, Cardner, Mathias, Beerenwinkel, Niko, Panke, Sven, Held, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904554/ https://www.ncbi.nlm.nih.gov/pubmed/35260685 http://dx.doi.org/10.1038/s41598-022-07755-7 |
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