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STAT6 Blockade Abrogates Aspergillus-Induced Eosinophilic Chronic Rhinosinusitis and Asthma, A Model of Unified Airway Disease

Unified airway disease, including concurrent asthma and chronic rhinosinusitis (CRS), is a common, but poorly understood disorder with no curative treatment options. To establish a murine model of chronic unified eosinophilic airway inflammation, mice were challenged with Aspergillus niger, and sino...

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Detalles Bibliográficos
Autores principales: Sun, Hua, Damania, Ashish, Mair, Megan L., Otukoya, Eniola, Li, Yi-Dong, Polsky, Katherine, Zeng, Yuying, Alt, Jeremiah A., Citardi, Martin J., Corry, David B., Luong, Amber U., Knight, John Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904741/
https://www.ncbi.nlm.nih.gov/pubmed/35281012
http://dx.doi.org/10.3389/fimmu.2022.818017