Clozapine Reverses Dysfunction of Glutamatergic Neurons Derived From Clozapine-Responsive Schizophrenia Patients

The cellular pathology of schizophrenia and the potential of antipsychotics to target underlying neuronal dysfunctions are still largely unknown. We employed glutamatergic neurons derived from induced pluripotent stem cells (iPSC) obtained from schizophrenia patients with known histories of response...

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Detalles Bibliográficos
Autores principales: Hribkova, Hana, Svoboda, Ondrej, Bartecku, Elis, Zelinkova, Jana, Horinkova, Jana, Lacinova, Lubica, Piskacek, Martin, Lipovy, Bretislav, Provaznik, Ivo, Glover, Joel C., Kasparek, Tomas, Sun, Yuh-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904748/
https://www.ncbi.nlm.nih.gov/pubmed/35281293
http://dx.doi.org/10.3389/fncel.2022.830757

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