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Automated pancreas segmentation and volumetry using deep neural network on computed tomography

Pancreas segmentation is necessary for observing lesions, analyzing anatomical structures, and predicting patient prognosis. Therefore, various studies have designed segmentation models based on convolutional neural networks for pancreas segmentation. However, the deep learning approach is limited b...

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Autores principales: Lim, Sang-Heon, Kim, Young Jae, Park, Yeon-Ho, Kim, Doojin, Kim, Kwang Gi, Lee, Doo-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904764/
https://www.ncbi.nlm.nih.gov/pubmed/35260710
http://dx.doi.org/10.1038/s41598-022-07848-3
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author Lim, Sang-Heon
Kim, Young Jae
Park, Yeon-Ho
Kim, Doojin
Kim, Kwang Gi
Lee, Doo-Ho
author_facet Lim, Sang-Heon
Kim, Young Jae
Park, Yeon-Ho
Kim, Doojin
Kim, Kwang Gi
Lee, Doo-Ho
author_sort Lim, Sang-Heon
collection PubMed
description Pancreas segmentation is necessary for observing lesions, analyzing anatomical structures, and predicting patient prognosis. Therefore, various studies have designed segmentation models based on convolutional neural networks for pancreas segmentation. However, the deep learning approach is limited by a lack of data, and studies conducted on a large computed tomography dataset are scarce. Therefore, this study aims to perform deep-learning-based semantic segmentation on 1006 participants and evaluate the automatic segmentation performance of the pancreas via four individual three-dimensional segmentation networks. In this study, we performed internal validation with 1,006 patients and external validation using the cancer imaging archive pancreas dataset. We obtained mean precision, recall, and dice similarity coefficients of 0.869, 0.842, and 0.842, respectively, for internal validation via a relevant approach among the four deep learning networks. Using the external dataset, the deep learning network achieved mean precision, recall, and dice similarity coefficients of 0.779, 0.749, and 0.735, respectively. We expect that generalized deep-learning-based systems can assist clinical decisions by providing accurate pancreatic segmentation and quantitative information of the pancreas for abdominal computed tomography.
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spelling pubmed-89047642022-03-10 Automated pancreas segmentation and volumetry using deep neural network on computed tomography Lim, Sang-Heon Kim, Young Jae Park, Yeon-Ho Kim, Doojin Kim, Kwang Gi Lee, Doo-Ho Sci Rep Article Pancreas segmentation is necessary for observing lesions, analyzing anatomical structures, and predicting patient prognosis. Therefore, various studies have designed segmentation models based on convolutional neural networks for pancreas segmentation. However, the deep learning approach is limited by a lack of data, and studies conducted on a large computed tomography dataset are scarce. Therefore, this study aims to perform deep-learning-based semantic segmentation on 1006 participants and evaluate the automatic segmentation performance of the pancreas via four individual three-dimensional segmentation networks. In this study, we performed internal validation with 1,006 patients and external validation using the cancer imaging archive pancreas dataset. We obtained mean precision, recall, and dice similarity coefficients of 0.869, 0.842, and 0.842, respectively, for internal validation via a relevant approach among the four deep learning networks. Using the external dataset, the deep learning network achieved mean precision, recall, and dice similarity coefficients of 0.779, 0.749, and 0.735, respectively. We expect that generalized deep-learning-based systems can assist clinical decisions by providing accurate pancreatic segmentation and quantitative information of the pancreas for abdominal computed tomography. Nature Publishing Group UK 2022-03-08 /pmc/articles/PMC8904764/ /pubmed/35260710 http://dx.doi.org/10.1038/s41598-022-07848-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lim, Sang-Heon
Kim, Young Jae
Park, Yeon-Ho
Kim, Doojin
Kim, Kwang Gi
Lee, Doo-Ho
Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title_full Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title_fullStr Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title_full_unstemmed Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title_short Automated pancreas segmentation and volumetry using deep neural network on computed tomography
title_sort automated pancreas segmentation and volumetry using deep neural network on computed tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904764/
https://www.ncbi.nlm.nih.gov/pubmed/35260710
http://dx.doi.org/10.1038/s41598-022-07848-3
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