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Senegenin Inhibits Aβ(1-42)-Induced PC12 Cells Apoptosis and Oxidative Stress via Activation of the PI3K/Akt Signaling Pathway

BACKGROUND/AIM: Apoptosis and oxidative stress have been considered as key events in the pathogenesis of Alzheimer’s disease (AD). Senegenin (Sen), the major and most effective ingredient of Radix Polygalae, which has anti-apoptotic and anti-oxidative effects. The aim of this study was to investigat...

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Detalles Bibliográficos
Autores principales:	Ren, Xing, Zhang, Jiwei, Zhao, Yunnan, Sun, Lingzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904946/ https://www.ncbi.nlm.nih.gov/pubmed/35280979 http://dx.doi.org/10.2147/NDT.S346238

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