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Sphingosine 1-phosphate receptor 1 governs endothelial barrier function and angiogenesis by upregulating endoglin signaling

BACKGROUND: The sphingosine 1-phosphate (S1P)/S1P receptor (S1pr) 1 signaling plays an essential role in regulating vascular integrity and angiogenesis. We have previously shown that cell-surface expression of endoglin (Eng) is sustained by S1P/S1pr1 signaling in endothelial cells (ECs). However, wh...

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Detalles Bibliográficos
Autores principales:	Wang, Beibei, Dong, Nian, Wu, Dengmin, Fang, Ya, Chen, Junjie, Lin, Yuting, Bellusci, Saverio, Zhang, Jin-San, Dai, Kezhi, Chen, Chengshui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904984/ https://www.ncbi.nlm.nih.gov/pubmed/35284541 http://dx.doi.org/10.21037/atm-21-6679

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