Cargando…
First-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants
SARS-CoV-2 and its variants have persisted in this ongoing COVID-19 pandemic. While the vaccines have greatly reduced the COVID-19 cases, hospitalizations, and death, about half of the world remain unvaccinated due to various reasons. Furthermore, the duration of the immunity gained from COVID-19 va...
Autores principales: | Titong, Allison, Gallolu Kankanamalage, Sachith, Dong, Jianbo, Huang, Betty, Spadoni, Nicholas, Wang, Bo, Wright, Meredith, Pham, Keegan L. J., Le, Anh Hai, Liu, Yue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905027/ https://www.ncbi.nlm.nih.gov/pubmed/35264679 http://dx.doi.org/10.1038/s41598-022-07952-4 |
Ejemplares similares
-
A novel IgG Fc by computer-aided design enhances heavy-chain heterodimerization in bi- or trispecific antibodies
por: Wang, Bo, et al.
Publicado: (2022) -
Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2
por: Dong, Jianbo, et al.
Publicado: (2020) -
Author Correction: Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2
por: Dong, Jianbo, et al.
Publicado: (2021) -
Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity
por: Dong, Jianbo, et al.
Publicado: (2020) -
Optimization of therapeutic antibodies
por: Wang, Bo, et al.
Publicado: (2021)