SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner

As one of the most common post-transcriptional modifications of mRNAs and noncoding RNAs, N(6)-methyladenosine (m(6)A) modification regulates almost every aspect of RNA metabolism. Evidence indicates that dysregulation of m(6)A modification and associated proteins contributes to glioblastoma (GBM) p...

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Detalles Bibliográficos
Autores principales: Zhang, Shouji, Zhao, Shulin, Qi, Yanhua, Li, Boyan, Wang, Huizhi, Pan, Ziwen, Xue, Hao, Jin, Chuandi, Qiu, Wei, Chen, Zihang, Guo, Qindong, Fan, Yang, Xu, Jianye, Gao, Zijie, Wang, Shaobo, Guo, Xing, Deng, Lin, Ni, Shilei, Xue, Fuzhong, Wang, Jian, Zhao, Rongrong, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905236/
https://www.ncbi.nlm.nih.gov/pubmed/35317283
http://dx.doi.org/10.1016/j.omtn.2021.12.035

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