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A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting TRPA1

Drug discovery from plants usually focuses on small molecules rather than such biological macromolecules as RNAs. Although plant transfer RNA (tRNA)-derived fragment (tRF) has been associated with the developmental and defense mechanisms in plants, its regulatory role in mammals remains unclear. By...

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Detalles Bibliográficos
Autores principales: Cao, Kai-Yue, Yan, Tong-Meng, Zhang, Ji-Zhou, Chan, Ting-Fung, Li, Jie, Li, Chong, Lai-Han Leung, Elaine, Gao, Jin, Zhang, Bao-Xian, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905250/
https://www.ncbi.nlm.nih.gov/pubmed/35317282
http://dx.doi.org/10.1016/j.omtn.2021.12.037