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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

Myocardial inflammation contributes to cardiomyopathy in diabetic patients through incompletely defined underlying mechanisms. In both human and time-course experimental samples, diabetic hearts exhibited abnormal ER, with a maladaptive shift over time in rodents. Furthermore, as a cardiac ER dysfun...

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Detalles Bibliográficos
Autores principales: Kaur, Namrita, Ruiz-Velasco, Andrea, Raja, Rida, Howell, Gareth, Miller, Jessica M., Abouleisa, Riham R.E., Ou, Qinghui, Mace, Kimberly, Hille, Susanne S., Frey, Norbert, Binder, Pablo, Smith, Craig P., Fachim, Helene, Soran, Handrean, Swanton, Eileithyia, Mohamed, Tamer M.A., Müller, Oliver J., Wang, Xin, Chernoff, Jonathan, Cartwright, Elizabeth J., Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905320/
https://www.ncbi.nlm.nih.gov/pubmed/35281739
http://dx.doi.org/10.1016/j.isci.2022.103973