Cargando…

Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material

The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the substance diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate, FCM substance No. 1007, which is intended to be used in the polymerisation reaction to make poly(ethylene 2,5‐fura...

Descripción completa

Detalles Bibliográficos
Autores principales: Lambré, Claude, Barat Baviera, José Manuel, Bolognesi, Claudia, Chesson, Andrew, Cocconcelli, Pier Sandro, Crebelli, Riccardo, Gott, David Michael, Grob, Konrad, Lampi, Evgenia, Mengelers, Marcel, Mortensen, Alicja, Steffensen, Inger‐Lise, Tlustos, Christina, Van Loveren, Henk, Vernis, Laurence, Zorn, Holger, Castle, Laurence, Di Consiglio, Emma, Franz, Roland, Hellwig, Nicole, Milana, Maria Rosaria, Merkel, Stefan, Barthélémy, Eric, Comandella, Daniele, Rivière, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905421/
https://www.ncbi.nlm.nih.gov/pubmed/35281645
http://dx.doi.org/10.2903/j.efsa.2022.7172
_version_ 1784665181840736256
author Lambré, Claude
Barat Baviera, José Manuel
Bolognesi, Claudia
Chesson, Andrew
Cocconcelli, Pier Sandro
Crebelli, Riccardo
Gott, David Michael
Grob, Konrad
Lampi, Evgenia
Mengelers, Marcel
Mortensen, Alicja
Steffensen, Inger‐Lise
Tlustos, Christina
Van Loveren, Henk
Vernis, Laurence
Zorn, Holger
Castle, Laurence
Di Consiglio, Emma
Franz, Roland
Hellwig, Nicole
Milana, Maria Rosaria
Merkel, Stefan
Barthélémy, Eric
Comandella, Daniele
Rivière, Gilles
author_facet Lambré, Claude
Barat Baviera, José Manuel
Bolognesi, Claudia
Chesson, Andrew
Cocconcelli, Pier Sandro
Crebelli, Riccardo
Gott, David Michael
Grob, Konrad
Lampi, Evgenia
Mengelers, Marcel
Mortensen, Alicja
Steffensen, Inger‐Lise
Tlustos, Christina
Van Loveren, Henk
Vernis, Laurence
Zorn, Holger
Castle, Laurence
Di Consiglio, Emma
Franz, Roland
Hellwig, Nicole
Milana, Maria Rosaria
Merkel, Stefan
Barthélémy, Eric
Comandella, Daniele
Rivière, Gilles
collection PubMed
description The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the substance diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate, FCM substance No. 1007, which is intended to be used in the polymerisation reaction to make poly(ethylene 2,5‐furandicarboxylate) (PEF) plastic. The substance is intended to become a component of the backbone of the polymer and has an antioxidant function that provides thermal stability to the polyester during heat processing. The resulting plastic is intended to be used in contact with all types of food under any condition of time and temperature. A PEF sample made using 0.1% w/w of the substance (which is the maximum intended use) was used in a comprehensive set of migration tests with food simulants. The migration of the substance was below the quantification limits estimated around 10 µg/kg. Solvent extraction tests showed no presence of impurities or breakdown products of the substance. The toxicological data provided are the same as those submitted by the same applicant and previously evaluated. The resulting assessment and conclusions are considered still valid by the CEP Panel. Therefore, the CEP Panel concluded that the substance diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl]phosphonate does not raise a safety concern for the consumer if used at up to 0.1% w/w (based on the weight of the polymer) in the polymerisation to make PEF intended for contact with all types of foods under any contact conditions.
format Online
Article
Text
id pubmed-8905421
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-89054212022-03-10 Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material Lambré, Claude Barat Baviera, José Manuel Bolognesi, Claudia Chesson, Andrew Cocconcelli, Pier Sandro Crebelli, Riccardo Gott, David Michael Grob, Konrad Lampi, Evgenia Mengelers, Marcel Mortensen, Alicja Steffensen, Inger‐Lise Tlustos, Christina Van Loveren, Henk Vernis, Laurence Zorn, Holger Castle, Laurence Di Consiglio, Emma Franz, Roland Hellwig, Nicole Milana, Maria Rosaria Merkel, Stefan Barthélémy, Eric Comandella, Daniele Rivière, Gilles EFSA J Scientific Opinion The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the substance diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate, FCM substance No. 1007, which is intended to be used in the polymerisation reaction to make poly(ethylene 2,5‐furandicarboxylate) (PEF) plastic. The substance is intended to become a component of the backbone of the polymer and has an antioxidant function that provides thermal stability to the polyester during heat processing. The resulting plastic is intended to be used in contact with all types of food under any condition of time and temperature. A PEF sample made using 0.1% w/w of the substance (which is the maximum intended use) was used in a comprehensive set of migration tests with food simulants. The migration of the substance was below the quantification limits estimated around 10 µg/kg. Solvent extraction tests showed no presence of impurities or breakdown products of the substance. The toxicological data provided are the same as those submitted by the same applicant and previously evaluated. The resulting assessment and conclusions are considered still valid by the CEP Panel. Therefore, the CEP Panel concluded that the substance diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl]phosphonate does not raise a safety concern for the consumer if used at up to 0.1% w/w (based on the weight of the polymer) in the polymerisation to make PEF intended for contact with all types of foods under any contact conditions. John Wiley and Sons Inc. 2022-03-09 /pmc/articles/PMC8905421/ /pubmed/35281645 http://dx.doi.org/10.2903/j.efsa.2022.7172 Text en © 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Lambré, Claude
Barat Baviera, José Manuel
Bolognesi, Claudia
Chesson, Andrew
Cocconcelli, Pier Sandro
Crebelli, Riccardo
Gott, David Michael
Grob, Konrad
Lampi, Evgenia
Mengelers, Marcel
Mortensen, Alicja
Steffensen, Inger‐Lise
Tlustos, Christina
Van Loveren, Henk
Vernis, Laurence
Zorn, Holger
Castle, Laurence
Di Consiglio, Emma
Franz, Roland
Hellwig, Nicole
Milana, Maria Rosaria
Merkel, Stefan
Barthélémy, Eric
Comandella, Daniele
Rivière, Gilles
Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title_full Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title_fullStr Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title_full_unstemmed Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title_short Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
title_sort safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905421/
https://www.ncbi.nlm.nih.gov/pubmed/35281645
http://dx.doi.org/10.2903/j.efsa.2022.7172
work_keys_str_mv AT safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT lambreclaude safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT baratbavierajosemanuel safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT bolognesiclaudia safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT chessonandrew safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT cocconcellipiersandro safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT crebelliriccardo safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT gottdavidmichael safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT grobkonrad safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT lampievgenia safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT mengelersmarcel safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT mortensenalicja safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT steffenseningerlise safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT tlustoschristina safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT vanloverenhenk safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT vernislaurence safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT zornholger safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT castlelaurence safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT diconsiglioemma safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT franzroland safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT hellwignicole safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT milanamariarosaria safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT merkelstefan safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT barthelemyeric safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT comandelladaniele safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial
AT rivieregilles safetyassessmentofdiethyl35bis11dimethylethyl4hydroxyphenylmethylphosphonateforuseinafoodcontactmaterial