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Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b inclu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905422/ https://www.ncbi.nlm.nih.gov/pubmed/35280716 http://dx.doi.org/10.1002/rcr2.919 |
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author | Horio, Yoshitsugu Tachibana, Hiroyuki Shimizu, Junichi Hosoda, Waki Fujiwara, Yutaka |
author_facet | Horio, Yoshitsugu Tachibana, Hiroyuki Shimizu, Junichi Hosoda, Waki Fujiwara, Yutaka |
author_sort | Horio, Yoshitsugu |
collection | PubMed |
description | Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b includes involvement of a single intrathoracic nonregional lymph node (LN) such as pericardial, internal mammary or paravertebral LNs. Here, we report a successful treated case of a 50‐year‐old female with ES‐SCLC with right pericardial LN involvement, cT1cN3M1b (LYM). She initially received two cycles of induction chemotherapy consisting of cis‐Diamminedichloroplatinum/cisplatin (CDDP) and etoposide and achieved a very good partial response. She then received curative chemoradiotherapy with intensity‐modulated techniques (45 Gy in 30 fractions BID), followed by an additional cycle of chemotherapy. She is free of recurrence for more than 2.5 years. |
format | Online Article Text |
id | pubmed-8905422 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-89054222022-03-10 Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer Horio, Yoshitsugu Tachibana, Hiroyuki Shimizu, Junichi Hosoda, Waki Fujiwara, Yutaka Respirol Case Rep Case Reports Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b includes involvement of a single intrathoracic nonregional lymph node (LN) such as pericardial, internal mammary or paravertebral LNs. Here, we report a successful treated case of a 50‐year‐old female with ES‐SCLC with right pericardial LN involvement, cT1cN3M1b (LYM). She initially received two cycles of induction chemotherapy consisting of cis‐Diamminedichloroplatinum/cisplatin (CDDP) and etoposide and achieved a very good partial response. She then received curative chemoradiotherapy with intensity‐modulated techniques (45 Gy in 30 fractions BID), followed by an additional cycle of chemotherapy. She is free of recurrence for more than 2.5 years. John Wiley & Sons, Ltd 2022-03-09 /pmc/articles/PMC8905422/ /pubmed/35280716 http://dx.doi.org/10.1002/rcr2.919 Text en © 2022 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Horio, Yoshitsugu Tachibana, Hiroyuki Shimizu, Junichi Hosoda, Waki Fujiwara, Yutaka Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title | Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title_full | Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title_fullStr | Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title_full_unstemmed | Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title_short | Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
title_sort | successful imrt and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905422/ https://www.ncbi.nlm.nih.gov/pubmed/35280716 http://dx.doi.org/10.1002/rcr2.919 |
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