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Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer

Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b inclu...

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Autores principales: Horio, Yoshitsugu, Tachibana, Hiroyuki, Shimizu, Junichi, Hosoda, Waki, Fujiwara, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905422/
https://www.ncbi.nlm.nih.gov/pubmed/35280716
http://dx.doi.org/10.1002/rcr2.919
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author Horio, Yoshitsugu
Tachibana, Hiroyuki
Shimizu, Junichi
Hosoda, Waki
Fujiwara, Yutaka
author_facet Horio, Yoshitsugu
Tachibana, Hiroyuki
Shimizu, Junichi
Hosoda, Waki
Fujiwara, Yutaka
author_sort Horio, Yoshitsugu
collection PubMed
description Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b includes involvement of a single intrathoracic nonregional lymph node (LN) such as pericardial, internal mammary or paravertebral LNs. Here, we report a successful treated case of a 50‐year‐old female with ES‐SCLC with right pericardial LN involvement, cT1cN3M1b (LYM). She initially received two cycles of induction chemotherapy consisting of cis‐Diamminedichloroplatinum/cisplatin (CDDP) and etoposide and achieved a very good partial response. She then received curative chemoradiotherapy with intensity‐modulated techniques (45 Gy in 30 fractions BID), followed by an additional cycle of chemotherapy. She is free of recurrence for more than 2.5 years.
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spelling pubmed-89054222022-03-10 Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer Horio, Yoshitsugu Tachibana, Hiroyuki Shimizu, Junichi Hosoda, Waki Fujiwara, Yutaka Respirol Case Rep Case Reports Treatment of extensive‐stage (ES) small cell lung cancer (SCLC) is a challenge with poor local control and dismal overall survival. Although single extrathoracic metastasis was defined as M1b according to the eighth edition of the tumour–node–metastasis (TNM) classification of lung cancer, M1b includes involvement of a single intrathoracic nonregional lymph node (LN) such as pericardial, internal mammary or paravertebral LNs. Here, we report a successful treated case of a 50‐year‐old female with ES‐SCLC with right pericardial LN involvement, cT1cN3M1b (LYM). She initially received two cycles of induction chemotherapy consisting of cis‐Diamminedichloroplatinum/cisplatin (CDDP) and etoposide and achieved a very good partial response. She then received curative chemoradiotherapy with intensity‐modulated techniques (45 Gy in 30 fractions BID), followed by an additional cycle of chemotherapy. She is free of recurrence for more than 2.5 years. John Wiley & Sons, Ltd 2022-03-09 /pmc/articles/PMC8905422/ /pubmed/35280716 http://dx.doi.org/10.1002/rcr2.919 Text en © 2022 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Horio, Yoshitsugu
Tachibana, Hiroyuki
Shimizu, Junichi
Hosoda, Waki
Fujiwara, Yutaka
Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title_full Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title_fullStr Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title_full_unstemmed Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title_short Successful IMRT and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
title_sort successful imrt and concurrent chemotherapy for a patient with intrathoracic extensive‐stage small cell lung cancer
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905422/
https://www.ncbi.nlm.nih.gov/pubmed/35280716
http://dx.doi.org/10.1002/rcr2.919
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